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Protein tyrosine phosphatase σ targets apical junction complex proteins in the intestine and regulates epithelial permeability
Protein tyrosine phosphatase (PTP)σ (PTPRS) was shown previously to be associated with susceptibility to inflammatory bowel disease (IBD). PTPσ(−/−) mice exhibit an IBD-like phenotype in the intestine and show increased susceptibility to acute models of murine colitis. However, the function of PTPσ...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3896190/ https://ncbi.nlm.nih.gov/pubmed/24385580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1315017111 |
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