Localization of αυβ6 Integrin-TGF-β1/Smad3, mTOR and PPARγ in Experimental Colorectal Fibrosis

A simultaneous action of several pro-fibrotic mediators appears relevant in the development of fibrosis. There are evidences that transforming growth factor-β (TGF-β)/Smad3 pathway forms with αvβ6 integrin, mammalian target of Rapamycin (mTOR) and peroxisome proliferator-activated receptor-γ (PPARγ)...

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Bibliographische Detailangaben
Hauptverfasser: Latella, G., Vetuschi, A., Sferra, R., Speca, S., Gaudio, E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: PAGEPress Publications, Pavia, Italy 2013
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Original Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896042/
https://ncbi.nlm.nih.gov/pubmed/24441193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4081/ejh.2013.e40
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