Decitabine impact on the endocytosis regulator RhoA, the folate carriers RFC1 and FOLR1, and the glucose transporter GLUT4 in human tumors

BACKGROUND: In 31 solid tumor patients treated with the demethylating agent decitabine, we performed tumor biopsies before and after the first cycle of decitabine and used immunohistochemistry (IHC) to assess whether decitabine increased expression of various membrane transporters. Resistance to che...

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Bibliografiska uppgifter
Huvudupphovsmän: Stewart, David J, Nunez, Maria I, Jelinek, Jaroslav, Hong, David, Gupta, Sanjay, Issa, Jean-Pierre, Wistuba, Ignacio I, Kurzrock, Razelle
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2014
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895853/
https://ncbi.nlm.nih.gov/pubmed/24401732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-6-2
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