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Murine esBAF chromatin remodeling complex subunits BAF250a and Brg1 are necessary to maintain and reprogram pluripotency-specific replication timing of select replication domains

BACKGROUND: Cellular differentiation and reprogramming are accompanied by changes in replication timing and 3D organization of large-scale (400 to 800 Kb) chromosomal domains (‘replication domains’), but few gene products have been identified whose disruption affects these properties. RESULTS: Here...

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Detalhes bibliográficos
Main Authors: Takebayashi, Shin-ichiro, Lei, Ienglam, Ryba, Tyrone, Sasaki, Takayo, Dileep, Vishnu, Battaglia, Dana, Gao, Xiaolin, Fang, Peng, Fan, Yong, Esteban, Miguel A, Tang, Jiong, Crabtree, Gerald R, Wang, Zhong, Gilbert, David M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895691/
https://ncbi.nlm.nih.gov/pubmed/24330833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-6-42
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