Acid evoked thermal hyperalgesia involves peripheral P2Y1 receptor mediated TRPV1 phosphorylation in a rodent model of thrombus induced ischemic pain

BACKGROUND: We previously developed a thrombus-induced ischemic pain (TIIP) animal model, which was characterized by chronic bilateral mechanical allodynia without thermal hyperalgesia (TH). On the other hand we had shown that intraplantar injection of acidic saline facilitated ATP-induced pain, whi...

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Detalhes bibliográficos
Main Authors: Kwon, Soon-Gu, Roh, Dae-Hyun, Yoon, Seo-Yeon, Moon, Ji-Young, Choi, Sheu-Ran, Choi, Hoon-Seong, Kang, Suk-Yun, Han, Ho-Jae, Beitz, Alvin J, Oh, Seog Bae, Lee, Jang-Hern
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895685/
https://ncbi.nlm.nih.gov/pubmed/24401144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-10-2
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