AMPK agonist AICAR improves cognition and motor coordination in young and aged mice

Normal aging can result in a decline of memory and muscle function. Exercise may prevent or delay these changes. However, aging-associated frailty can preclude physical activity. In young sedentary animals, pharmacological activation of AMP-activated protein kinase (AMPK), a transcriptional regulato...

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Detalhes bibliográficos
Main Authors: Kobilo, Tali, Guerrieri, Davide, Zhang, Yongqing, Collica, Sarah C., Becker, Kevin G., van Praag, Henriette
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895225/
https://ncbi.nlm.nih.gov/pubmed/24443745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.033332.113
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