The AMPK Agonist AICAR Inhibits TGF-β1 Induced Activation of Kidney Myofibroblasts

Activation of interstitial myofibroblasts and excessive production of extracellular matrix proteins are common pathways that contribute to chronic kidney disease. In a number of tissues, AMP-activated kinase (AMPK) activation has been shown to inhibit fibrosis. Here, we examined the inhibitory effec...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chen, Kuan-Hsing, Hsu, Hsiang-Hao, Lee, Cheng-Chia, Yen, Tzu-Hai, Ko, Yi-Ching, Yang, Chih-Wei, Hung, Cheng-Chieh
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2014
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154690/
https://ncbi.nlm.nih.gov/pubmed/25188319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106554
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