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Activity-dependent changes in MAPK activation in the Angelman Syndrome mouse model

Angelman Syndrome (AS) is a devastating neurological disorder caused by disruption of the maternal UBE3A gene. Ube3a protein is identified as an E3 ubiquitin ligase that shows neuron-specific imprinting. Despite extensive research evaluating the localization and basal expression profiles of Ube3a in...

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Bibliografske podrobnosti
Main Authors: Filonova, Irina, Trotter, Justin H., Banko, Jessica L., Weeber, Edwin J.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895224/
https://ncbi.nlm.nih.gov/pubmed/24434871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.032375.113
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