Angiopoietin-Like Protein 2 Induced by Mechanical Stress Accelerates Degeneration and Hypertrophy of the Ligamentum Flavum in Lumbar Spinal Canal Stenosis

Chronic inflammation and subsequent fibrosis induced by mechanical stress play an important role in ligamentum flavum (LF) hypertrophy and degeneration in patients with lumbar spinal canal stenosis (LSCS). Angiopoietin-like protein 2 (Angptl2) is a chronic inflammatory mediator induced under various...

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Detalhes bibliográficos
Main Authors: Nakamura, Takayuki, Okada, Tatsuya, Endo, Motoyoshi, Kadomatsu, Tsuyoshi, Taniwaki, Takuya, Sei, Akira, Odagiri, Haruki, Masuda, Tetsuro, Fujimoto, Toru, Nakamura, Takafumi, Oike, Yuichi, Mizuta, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894965/
https://ncbi.nlm.nih.gov/pubmed/24465594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085542
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