Mice Deficient in Angiopoietin-like Protein 2 (Angptl2) Gene Show Increased Susceptibility to Bacterial Infection Due to Attenuated Macrophage Activity

Macrophages play crucial roles in combatting infectious disease by promoting inflammation and phagocytosis. Angiopoietin-like protein 2 (ANGPTL2) is a secreted factor that induces tissue inflammation by attracting and activating macrophages to produce inflammatory cytokines in chronic inflammation-a...

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Udgivet i:J Biol Chem
Main Authors: Yugami, Masaki, Odagiri, Haruki, Endo, Motoyoshi, Tsutsuki, Hiroyasu, Fujii, Shigemoto, Kadomatsu, Tsuyoshi, Masuda, Tetsuro, Miyata, Keishi, Terada, Kazutoyo, Tanoue, Hironori, Ito, Hitoshi, Morinaga, Jun, Horiguchi, Haruki, Sugizaki, Taichi, Akaike, Takaaki, Gotoh, Tomomi, Takai, Toshiyuki, Sawa, Tomohiro, Mizuta, Hiroshi, Oike, Yuichi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2016
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009257/
https://ncbi.nlm.nih.gov/pubmed/27402837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.720870
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