Randomized phase II trial comparing two dose levels of thymoglobulin in patients undergoing unrelated donor hematopoietic cell transplantation

The optimal dose and schedule of thymoglobulin (ATG) for graft-versus-host disease prevention (GVHD) is unknown. We compared two doses of ATG (4.5 mg/kg and 7.5 mg/kg) in a Bayesian adaptively randomized fashion, and assessed whether ATG levels measured on days 0, 7, 14, and 28 were associated with...

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Detalhes bibliográficos
Main Authors: Bashir, Qaiser, Munsell, Mark F, Giralt, Sergio, de Padua Silva, Leandro, Sharma, Manish, Couriel, Daniel, Chiattone, Alexandre, Popat, Uday, Qazilbash, Muzaffar H, Fernandez-Vina, Marcelo, Champlin, Richard E, de Lima, Marcos J
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894827/
https://ncbi.nlm.nih.gov/pubmed/22023525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2011.634039
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