Prophylaxis of Graft-Versus-Host Disease in Unrelated Donor Transplantation With Pentostatin, Tacrolimus, and Mini-Methotrexate: A Phase I/II Controlled, Adaptively Randomized Study

PURPOSE: Acute graft-versus-host disease (aGVHD) is a major cause of morbidity and mortality after matched unrelated, related, or mismatched related donor hematopoietic stem-cell transplantation (HSCT). Improved GVHD prevention methods are needed. Pentostatin, an adenosine deaminase inhibitor, leads...

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Detalhes bibliográficos
Main Authors: Parmar, Simrit, Andersson, Borje S., Couriel, Daniel, Munsell, Mark F., Fernandez-Vina, Marcelo, Jones, Roy B., Shpall, Elizabeth J., Popat, Uday, Anderlini, Paolo, Giralt, Sergio, Alousi, Amin, Cano, Pedro, Bosque, Doyle, Hosing, Chitra, de Padua Silva, Leandro, Westmoreland, Michael, Wathen, J. Kyle, Berry, Donald, Champlin, Richard E., de Lima, Marcos J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2011
Assuntos:
Original Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056464/
https://ncbi.nlm.nih.gov/pubmed/21149654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2010.30.6357
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