Noggin Attenuates Cerulein-Induced Acute Pancreatitis and the Impaired Autophagy

OBJECTIVES: To investigate the role of bone morphogenetic protein (BMP) signaling in acute pancreatitis (AP) by administration of noggin, an endogenous BMP antagonist, in a cerulein-induced AP model. METHODS: AP was induced by 9 hourly intraperitoneal injections of cerulein (50 µg/kg). Control mice...

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Hlavní autoři: Cao, Yanna, Yang, Wenli, Tyler, Matthew A., Gao, Xuxia, Duan, Chaojun, Kim, Sung O., Aronson, Judith F., Popov, Vsevolod, Takahashi, Hitoshi, Saito, Hiroshi, Evers, B. Mark, Chao, Celia, Hellmich, Mark R., Ko, Tien C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894737/
https://ncbi.nlm.nih.gov/pubmed/22850625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0b013e31825b9f2c
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