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BMP2 inhibits TGF-β-induced pancreatic stellate cell activation and extracellular matrix formation
Activation of pancreatic stellate cells (PSCs) by transforming growth factor (TGF)-β is the key step in the development of pancreatic fibrosis, a common pathological feature of chronic pancreatitis (CP). Bone morphogenetic proteins (BMPs), members of the TGF-β superfamily, have anti-fibrogenic funct...
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| Asıl Yazarlar: | , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Physiological Society
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3652003/ https://ncbi.nlm.nih.gov/pubmed/23429583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00306.2012 |
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