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Clozapine, a Fast-Off-D2 Antipsychotic

[Image: see text] Ever since clozapine was first synthesized and tested, it showed the unique property of having antipsychotic action but no Parkinson-like motor side effects. The antipsychotic basis of clozapine is to transiently occupy dopamine D2 receptors in the human striatum, in contrast to ha...

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Главный автор: Seeman, Philip
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society 2013
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894721/
https://ncbi.nlm.nih.gov/pubmed/24219174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn400189s
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