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Association of sirolimus adverse effects with m-TOR, p70S6K or Raptor polymorphisms in kidney transplant recipients
The m-TOR inhibitor sirolimus is an immunosuppressive drug used in kidney transplantation. m-TOR binds with Raptor and phosphorylates p70S6 kinase, a protein involved in numerous cell signalling pathways. We investigated the association of candidate polymorphisms in m-TOR, Raptor and p70S6K, sirolim...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Lippincott Williams & Wilkins
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3894420/ https://ncbi.nlm.nih.gov/pubmed/22863900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e328357359d |
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