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Kinetics of promoter Pol II on Hsp70 reveal stable pausing and key insights into its regulation

The kinetics with which promoter-proximal paused RNA polymerase II (Pol II) undergoes premature termination versus productive elongation is central to understanding underlying mechanisms of metazoan transcription regulation. To assess the fate of Pol II quantitatively, we tracked photoactivatable GF...

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Detalhes bibliográficos
Main Authors: Buckley, Martin S., Kwak, Hojoong, Zipfel, Warren R., Lis, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894409/
https://ncbi.nlm.nih.gov/pubmed/24395245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.231886.113
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