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Cuz1/Ynl155w, a Zinc-dependent Ubiquitin-binding Protein, Protects Cells from Metalloid-induced Proteotoxicity

Protein misfolding is a universal threat to cells. The ubiquitin-proteasome system mediates a cellular stress response capable of eliminating misfolded proteins. Here we identify Cuz1/Ynl155w as a component of the ubiquitin system, capable of interacting with both the proteasome and Cdc48. Cuz1/Ynl1...

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Detalhes bibliográficos
Main Authors: Hanna, John, Waterman, David, Isasa, Marta, Elsasser, Suzanne, Shi, Yuan, Gygi, Steven, Finley, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894362/
https://ncbi.nlm.nih.gov/pubmed/24297164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.534032
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