Matrilin-1 Is Essential for Zebrafish Development by Facilitating Collagen II Secretion

Matrilin-1 is the prototypical member of the matrilin protein family and is highly expressed in cartilage. However, gene targeting of matrilin-1 in mouse did not lead to pronounced phenotypes. Here we used the zebrafish as an alternative model to study matrilin function in vivo. Matrilin-1 displays...

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Autori principali: Neacsu, Cristian Dan, Ko, Ya-Ping, Tagariello, Andreas, Røkenes Karlsen, Kristina, Neiss, Wolfram Friedrich, Paulsson, Mats, Wagener, Raimund
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
Soggetti:
Glycobiology and Extracellular Matrices
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894332/
https://ncbi.nlm.nih.gov/pubmed/24293366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.529933
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