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Probing the Dynamic Distribution of Bound States for Methylcytosine-binding Domains on DNA

Although highly homologous to other methylcytosine-binding domain (MBD) proteins, MBD3 does not selectively bind methylated DNA, and thus the functional role of MBD3 remains in question. To explore the structural basis of its binding properties and potential function, we characterized the solution s...

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Detalhes bibliográficos
Main Authors: Cramer, Jason M., Scarsdale, J. Neel, Walavalkar, Ninad M., Buchwald, William A., Ginder, Gordon D., Williams, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894315/
https://ncbi.nlm.nih.gov/pubmed/24307175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.512236
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