Loading...

Locally-generated Acetaldehyde Contributes to the Effects of Ethanol on Neurosteroids and LTP in the Hippocampus

BACKGROUND: As severe alcohol intoxication impairs memory function, a high concentration of ethanol (60 mM) acutely inhibits long-term potentiation (LTP), a cellular model of learning and memory, in rat hippocampal slices. Neurosteroids are involved in this LTP inhibition. We recently reported that...

Full description

Saved in:
Bibliographic Details
Main Authors: Tokuda, Kazuhiro, Izumi, Yukitoshi, Zorumski, Charles F.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894059/
https://ncbi.nlm.nih.gov/pubmed/24455167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ncn3.39
Tags: Add Tag
No Tags, Be the first to tag this record!