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Adenosine 3′:5′-Cyclic Monophosphate Concentration in the Bacterial Host Regulates the Viral Decision between Lysogeny and Lysis

Mutants of Salmonella typhimurium defective in adenylate cyclase (cya gene) or in cAMP receptor protein (crp gene) are lysogenized at reduced frequency by phage P22. One class of the bacterial mutants with an altered RNA polymerase (rif gene) is also lysogenized at reduced frequency. In the three ty...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Hong, Jen-Shiang, Smith, Gerald R., Ames, Bruce N.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1971
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389396/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4332251/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.9.2258
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