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Cyclic Guanosine Monophosphate–Adenosine Monophosphate Synthase (cGAS), a Multifaceted Platform of Intracellular DNA Sensing

Innate immune pathways are the first line of cellular defense against pathogen infections ranging from bacteria to Metazoa. These pathways are activated following the recognition of pathogen associated molecular patterns (PAMPs) by membrane and cytosolic pattern recognition receptors. In addition, s...

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Autori principali: Eloi R. Verrier, Christelle Langevin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021-02-01
Serie:Frontiers in Immunology
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Accesso online:https://www.frontiersin.org/articles/10.3389/fimmu.2021.637399/full
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