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A Novel Closed-Circular Mitochondrial DNA with Properties of a Replicating Intermediate

A fraction of the covalently closed mitochondrial DNA in mouse L cells contains a replicated heavy-strand segment that is hydrogen bonded to the circular light strand. The inserted single strand is dissociable from the circular duplex at an elevated temperature. IMAGES:

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Kasamatsu, Harumi, Robberson, Donald L., Vinograd, Jerome
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1971
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389395/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5289384/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.9.2252
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