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Enhanced Release of Dopamine-β-Hydroxylase from Sympathetic Nerves by Calcium and Phenoxybenzamine and Its Reversal by Prostaglandins

Dopamine-β-hydroxylase (EC 1.14.2.1), an enzyme localized in sympathetic synaptic vesicles, was released together with norepinephrine during in vitro stimulation of the hypogastric nerve that innervates the vas deferens of the guinea pig. Stimulation of the nerve in the presence of high concentratio...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Johnson, David G., Thoa, Nguyen B., Weinshilboum, Richard, Axelrod, Julius, Kopin, Irwin J.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1971
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389390/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5289380/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.9.2227
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