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Enhanced Release of Dopamine-β-Hydroxylase from Sympathetic Nerves by Calcium and Phenoxybenzamine and Its Reversal by Prostaglandins

Dopamine-β-hydroxylase (EC 1.14.2.1), an enzyme localized in sympathetic synaptic vesicles, was released together with norepinephrine during in vitro stimulation of the hypogastric nerve that innervates the vas deferens of the guinea pig. Stimulation of the nerve in the presence of high concentratio...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Johnson, David G., Thoa, Nguyen B., Weinshilboum, Richard, Axelrod, Julius, Kopin, Irwin J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1971
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389390/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5289380/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.9.2227
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