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Immune complex formation impairs the elimination of solutes from the brain: implications for immunotherapy in Alzheimer’s disease
BACKGROUND: Basement membranes in the walls of cerebral capillaries and arteries form a major lymphatic drainage pathway for fluid and solutes from the brain. Amyloid-β (Aβ) draining from the brain is deposited in such perivascular pathways as cerebral amyloid angiopathy (CAA) in Alzheimer's di...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3893559/ https://ncbi.nlm.nih.gov/pubmed/24252464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-1-48 |
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