Nuclear protein import: Ran-GTP dissociates the karyopherin alphabeta heterodimer by displacing alpha from an overlapping binding site on beta.

The alpha subunit of the karyopherin heterodimer functions in recognition of the protein import substrate and the beta subunit serves to dock the trimeric complex to one of many sites on nuclear pore complex fibers. The small GTPase Ran and the Ran interactive protein, p10, function in the release o...

Full description

Saved in:
Bibliographic Details
Main Authors: Moroianu, J, Blobel, G, Radu, A
Format: Artigo
Language:Inglês
Published: 1996
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC38935/
https://ncbi.nlm.nih.gov/pubmed/8692944
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items