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An Efficient Large-Scale Retroviral Transduction Method Involving Preloading the Vector into a RetroNectin-Coated Bag with Low-Temperature Shaking

In retroviral vector-mediated gene transfer, transduction efficiency can be hampered by inhibitory molecules derived from the culture fluid of virus producer cell lines. To remove these inhibitory molecules to enable better gene transduction, we had previously developed a transduction method using a...

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Detalhes bibliográficos
Main Authors: Dodo, Katsuyuki, Chono, Hideto, Saito, Naoki, Tanaka, Yoshinori, Tahara, Kenichi, Nukaya, Ikuei, Mineno, Junichi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3893289/
https://ncbi.nlm.nih.gov/pubmed/24454964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086275
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