Aspergillus nidulans Cell Wall Composition and Function Change in Response to Hosting Several Aspergillus fumigatus UDP-Galactopyranose Mutase Activity Mutants

Deletion or repression of Aspergillus nidulans ugmA (AnugmA), involved in galactofuranose biosynthesis, impairs growth and increases sensitivity to Caspofungin, a β-1,3-glucan synthesis antagonist. The A. fumigatus UgmA (AfUgmA) crystal structure has been determined. From that study, AfUgmA mutants...

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Main Authors: Alam, Md Kausar, van Straaten, Karin E., Sanders, David A. R., Kaminskyj, Susan G. W.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2014
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3893270/
https://ncbi.nlm.nih.gov/pubmed/24454924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085735
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