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Structural Insight into the Unique Substrate Binding Mechanism and Flavin Redox State of UDP-galactopyranose Mutase from Aspergillus fumigatus

UDP-galactopyranose mutase (UGM) is a flavin-containing enzyme that catalyzes the reversible conversion of UDP-galactopyranose (UDP-Galp) to UDP-galactofuranose (UDP-Galf). As in prokaryotic UGMs, the flavin needs to be reduced for the enzyme to be active. Here we present the first eukaryotic UGM st...

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Detalhes bibliográficos
Main Authors: van Straaten, Karin E., Routier, Françoise H., Sanders, David A. R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322874/
https://ncbi.nlm.nih.gov/pubmed/22334662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.322974
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