Transgenic Expression of Soluble Human CD5 Enhances Experimentally-Induced Autoimmune and Anti-Tumoral Immune Responses

CD5 is a lymphoid-specific transmembrane glycoprotein constitutively expressed on thymocytes and mature T and B1a lymphocytes. Current data support the view that CD5 is a negative regulator of antigen-specific receptor-mediated signaling in these cells, and that this would likely be achieved through...

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Main Authors: Fenutría, Rafael, Martinez, Vanesa G., Simões, Inês, Postigo, Jorge, Gil, Victor, Martínez-Florensa, Mario, Sintes, Jordi, Naves, Rodrigo, Cashman, Kevin S., Alberola-Ila, José, Ramos-Casals, Manel, Soldevila, Gloria, Raman, Chander, Merino, Jesús, Merino, Ramón, Engel, Pablo, Lozano, Francisco
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3893160/
https://ncbi.nlm.nih.gov/pubmed/24454761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084895
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