Multifaceted effects of soluble human CD6 in experimental cancer models

BACKGROUND: CD6 is a lymphocyte surface co-receptor physically associated with the T-cell receptor (TCR)/CD3 complex at the center of the immunological synapse. There, CD6 assists in cell-to-cell contact stabilization and modulation of activation/differentiation events through interaction with CD166...

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Veröffentlicht in:J Immunother Cancer
Hauptverfasser: Simões, Inês T, Aranda, Fernando, Casadó-Llombart, Sergi, Velasco-de Andrés, María, Català, Cristina, Álvarez, Pilar, Consuegra-Fernández, Marta, Orta-Mascaró, Marc, Merino, Ramón, Merino, Jesús, Alberola-Ila, José, González-Aseguinolaza, Gloria, Carreras, Esther, Martínez, Vanesa, Lozano, Francisco
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2020
Schlagworte:
Basic Tumor Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7174071/
https://ncbi.nlm.nih.gov/pubmed/32217757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2019-000172
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