A Modified Surface Killing Assay (MSKA) as a Functional in vitro Assay for Identifying Protective Antibodies Against Pneumococcal Surface Protein A (PspA)

Streptococcus pneumoniae causes otitis media, meningitis and pneumonia in patients worldwide; predominantly affecting young children, the elderly, and the immune compromised. Current vaccines against invasive pneumococcal disease are based on the polysaccharide capsules of the most clinically releva...

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Main Authors: Genschmer, Kristopher R., Accavitti-Loper, Mary Ann, Briles, David E.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3893085/
https://ncbi.nlm.nih.gov/pubmed/24211169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2013.10.080
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