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G-quadruplex-generating PCR for visual colorimetric detection of amplicons
We have developed a self-reporting PCR system for visual colorimetric gene detection and distinction of single nucleotide polymorphisms (SNP). Amplification is performed using target-specific primers modified with a 5’-end tail that is complementary to a G-quadruplex deoxyribozyme-forming sequence....
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3893031/ https://ncbi.nlm.nih.gov/pubmed/24135653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2013.10.010 |
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