Modulation of mutagenesis in eukaryotes by DNA replication fork dynamics and quality of nucleotide pools

The rate of mutations in eukaryotes depends on a plethora of factors and is not immediately derived from the fidelity of DNA polymerases (Pols). Replication of chromosomes containing the anti-parallel strands of duplex DNA occurs through the copying of leading and lagging strand templates by a trio...

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Hauptverfasser: Waisertreiger, Irina S.-R., Liston, Victoria G., Menezes, Miriam R., Kim, Hyun-Min, Lobachev, Kirill S., Stepchenkova, Elena I., Tahirov, Tahir H., Rogozin, Igor B., Pavlov, Youri. I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3893020/
https://ncbi.nlm.nih.gov/pubmed/23055184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.21735
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