The Mos/mitogen-activated protein kinase (MAPK) pathway regulates the size and degradation of the first polar body in maturing mouse oocytes.

Mos is an upstream activator of mitogen-activated protein kinase (MAPK) and, in mouse oocytes, is responsible for metaphase II arrest. This activity has been likened to its function in Xenopus oocytes as a component of cytostatic factor. Thus, Mos-deficient female mice (MOS-/-) are less fertile and...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Choi, T, Fukasawa, K, Zhou, R, Tessarollo, L, Borror, K, Resau, J, Vande Woude, G F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38930/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8692939/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.14.7032
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