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The Mos/mitogen-activated protein kinase (MAPK) pathway regulates the size and degradation of the first polar body in maturing mouse oocytes.

Mos is an upstream activator of mitogen-activated protein kinase (MAPK) and, in mouse oocytes, is responsible for metaphase II arrest. This activity has been likened to its function in Xenopus oocytes as a component of cytostatic factor. Thus, Mos-deficient female mice (MOS-/-) are less fertile and...

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Detalhes bibliográficos
Main Authors: Choi, T, Fukasawa, K, Zhou, R, Tessarollo, L, Borror, K, Resau, J, Vande Woude, G F
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC38930/
https://ncbi.nlm.nih.gov/pubmed/8692939
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