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Profiling targets of the irreversible palmitoylation inhibitor 2-bromopalmitate

2-bromohexadecanoic acid, or 2-bromopalmitate, was introduced nearly 50 years ago as a non-selective inhibitor of lipid metabolism. More recently, 2-bromopalmitate re-emerged as a general inhibitor of protein S-palmitoylation. Here, we investigate the cellular targets of 2-bromopalmitate through the...

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Bibliografske podrobnosti
Main Authors: Davda, Dahvid, El Azzouny, Mahmoud A., Tom, Christopher T.M.B., Hernandez, Jeannie L., Majmudar, Jaimeen D., Kennedy, Robert T., Martin, Brent R.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892994/
https://ncbi.nlm.nih.gov/pubmed/23844586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400380s
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