Cargando...

EndoU is a novel regulator of AICD during peripheral B cell selection

Balanced transmembrane signals maintain a competent peripheral B cell pool limited in self-reactive B cells that may produce pathogenic autoantibodies. To identify molecules regulating peripheral B cell survival and tolerance to self-antigens (Ags), a gene modifier screen was performed with B cells...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Poe, Jonathan C., Kountikov, Evgueni I., Lykken, Jacquelyn M., Natarajan, Abirami, Marchuk, Douglas A., Tedder, Thomas F.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892980/
https://ncbi.nlm.nih.gov/pubmed/24344237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20130648
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!