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EndoU is a novel regulator of AICD during peripheral B cell selection

Balanced transmembrane signals maintain a competent peripheral B cell pool limited in self-reactive B cells that may produce pathogenic autoantibodies. To identify molecules regulating peripheral B cell survival and tolerance to self-antigens (Ags), a gene modifier screen was performed with B cells...

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Detalles Bibliográficos
Main Authors: Poe, Jonathan C., Kountikov, Evgueni I., Lykken, Jacquelyn M., Natarajan, Abirami, Marchuk, Douglas A., Tedder, Thomas F.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892980/
https://ncbi.nlm.nih.gov/pubmed/24344237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20130648
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