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EndoU is a novel regulator of AICD during peripheral B cell selection
Balanced transmembrane signals maintain a competent peripheral B cell pool limited in self-reactive B cells that may produce pathogenic autoantibodies. To identify molecules regulating peripheral B cell survival and tolerance to self-antigens (Ags), a gene modifier screen was performed with B cells...
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Hauptverfasser: | , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
The Rockefeller University Press
2014
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3892980/ https://ncbi.nlm.nih.gov/pubmed/24344237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20130648 |
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