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A Fraction of the Ventricular Myocardium That Has the Specificity of the Cardiac Beta-Adrenergic Receptor

The 78,000 × g microsomal fraction of canine ventricular myocardium effected a 20-fold concentration of [(3)H]norepinephrine from a 10(-9) M solution. The [(3)H]norepinephrine bound was displaced by physiologic concentrations of the beta-adrenergic catecholamines isoproterenol, epinephrine, and nore...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Lefkowitz, Robert J., Haber, Edgar
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1971
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389290/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4399664/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.8.1773
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