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Rapidly Reversible Manipulation of Molecular Activities Using Dual Chemical Dimerizers
[Image: see text] The rapid, inducible, reversible modulation of molecular activities by dual CID systems. Rapamycin (Rapa) treatment induces relocation of FRB-POI to the GAIs-FKBP-C2(LACT)-labeled plasma membrane and activates POI-dependent signaling event. A subsequent GA(3)-AM treatment induces s...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3892897/ https://ncbi.nlm.nih.gov/pubmed/23649661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201301219 |
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