Characterization of hERG1 channel role in mouse colorectal carcinogenesis

The human ether-à-go-go-related gene (hERG)1 K(+) channel is upregulated in human colorectal cancer cells and primary samples. In this study, we examined the role of hERG1 in colorectal carcinogenesis using two mouse models: adenomatous polyposis coli (Apc(min/+)) and azoxymethane (AOM)-treated mice...

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Detalhes bibliográficos
Main Authors: Fiore, Antonella, Carraresi, Laura, Morabito, Angela, Polvani, Simone, Fortunato, Angelo, Lastraioli, Elena, Femia, Angelo P, Lorenzo, Emanuele, Caderni, Giovanna, Arcangeli, Annarosa
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Cancer Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892791/
https://ncbi.nlm.nih.gov/pubmed/24403225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.72
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