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A Translocation-Associated Ribosomal Conformation Change Detected by Hydrogen Exchange and Sedimentation Velocity

Translocation in ribosomes consists of transposition of peptidyl-tRNA from the aminoacyl to the peptidyl site and, probably concomitantly, the movement of ribosomes on mRNA. Does a conformational change in the ribosome provide the motive force for this process? Hydrogen exchange and sedimentation ve...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Chuang, De-Maw, Simpson, Melvin V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1971
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389221/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4934519/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.7.1474
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