Lentiviral Nef suppresses iron uptake in a strain specific manner through inhibition of Transferrin endocytosis

BACKGROUND: Increased cellular iron levels are associated with high mortality in HIV-1 infection. Moreover iron is an important cofactor for viral replication, raising the question whether highly divergent lentiviruses actively modulate iron homeostasis. Here, we evaluated the effect on cellular iro...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Koppensteiner, Herwig, Höhne, Kristin, Gondim, Marcos Vinicius, Gobert, Francois-Xavier, Widder, Miriam, Gundlach, Swantje, Heigele, Anke, Kirchhoff, Frank, Winkler, Michael, Benaroch, Philippe, Schindler, Michael
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892060/
https://ncbi.nlm.nih.gov/pubmed/24383984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-11-1
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker