Binding site size limit of the 2:1 pyrrole-imidazole polyamide-DNA motif.
Polyamides containing N-methylimidazole (Im) and N-methylpyrrole (Py) amino acids can be combined in antiparallel side-by-side dimeric complexes for sequence-specific recognition in the minor groove of DNA. Six polyamides containing three to eight rings bind DNA sites 5-10 bp in length, respectively...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38920/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8692930/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.14.6981 |
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