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Preconditioning with soluble guanylate cyclase activation prevents postischemic inflammation and reduces nitrate tolerance in heme oxygenase-1 knockout mice
Previously we have shown that, unlike wild-type mice (WT), heme oxygenase-1 knockout (HO-1(−/−)) mice developed nitrate tolerance and were not protected from inflammation caused by ischemia-reperfusion (I/R) when preconditioned with a H(2)S donor. We hypothesized that stimulation (with BAY 41-2272)...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3891245/ https://ncbi.nlm.nih.gov/pubmed/23771693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00810.2012 |
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