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Chenodeoxycholic acid stimulates Cl(−) secretion via cAMP signaling and increases cystic fibrosis transmembrane conductance regulator phosphorylation in T84 cells

High levels of chenodeoxycholic acid (CDCA) and deoxycholic acid stimulate Cl(−) secretion in mammalian colonic epithelia. While different second messengers have been implicated in this action, the specific signaling pathway has not been fully delineated. Using human colon carcinoma T84 cells, we el...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Ao, Mei, Sarathy, Jayashree, Domingue, Jada, Alrefai, Waddah A., Rao, Mrinalini C.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Physiological Society 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891218/
https://ncbi.nlm.nih.gov/pubmed/23761628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00416.2012
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