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Molecular interaction between natural IgG and ficolin – mechanistic insights on adaptive-innate immune crosstalk

Recently, we found that natural IgG (nIgG; a non-specific immunoglobulin of adaptive immunity) is not quiescent, but plays a crucial role in immediate immune defense by collaborating with ficolin (an innate immune protein). However, how the nIgG and ficolin interplay and what factors control the com...

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Bibliografiske detaljer
Main Authors: Panda, Saswati, Zhang, Jing, Yang, Lifeng, Anand, Ganesh S., Ding, Jeak L.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891018/
https://ncbi.nlm.nih.gov/pubmed/24419227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03675
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